NTSR2 Antikörper (AA 151-250)

Produktnummer ABIN1386651

Dieser Anti-NTSR2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von NTSR2 in WB, ELISA, IF (cc), IF (p), IHC (p), ICC und IHC (fro). Geeignet für Maus.

Kurzübersicht für NTSR2 Antikörper (AA 151-250) (ABIN1386651)

Target: NTSR2 (Neurotensin Receptor 2 (NTSR2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NTSR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NTSR2 Antikörper

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neurotensin Receptor 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NTSR2

Target: NTSR2 (Neurotensin Receptor 2 (NTSR2))

Andere Bezeichnung: Neurotensin Receptor 2

Hintergrund:

Synonyms: Levocabastine sensitive neurotensin receptor, Levocabastine-sensitive neurotensin receptor, Neurotensin receptor type 2, NT R 2, NT-R-2, NTR2, NTR2 receptor, NTR2_HUMAN, Ntsr2.

Background: Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner.